neurotoxins at NM Aesthetics

TOX: Botox vs Dysport vs Xeomin vs Jeuveau vs. Daxxify

At NM Aesthetics, the top injectors in Arlington, VA, one of the most popular non-surgical treatments we offer is neurotoxin injections like Botox, Dysport, Xeomin, Jeuveau and Daxxify. While these injectables all work by temporarily paralyzing facial muscles to reduce the appearance of lines and wrinkles, there are some key differences worth understanding.

In this guide, we'll break down everything you need to know about Botox, Dysport, Xeomin, Jeuveau and Daxxify so you can decide which option might be best suited for you. Request an appointment today with our board certified medical providers in Arlington, VA today to create your customized plan for your best results. 


You've likely heard of Botox (onabotulinumtoxinA) - it's been around since the 1970s and was initially approved In 1989 by the US Food and Drug Administration (FDA) to treat strabismus and blepharospasm, before later being used in aesthetic medicine. Botox contains botulinum toxin A, which blocks signals from nerves to muscles to reduce muscle contractions that cause dynamic wrinkles like crow's feet, forehead lines, and the 11s between the brows.  

Botox can smooth existing lines while preventing deeper etched-in lines from forming over time if used as a preventative measure. Results typically last 3-4 months before the muscles start contracting again as the Botox wears off. Most patients get injections 3-4 times per year to maintain results.


Like Botox, Dysport (abobotulinumtoxinA) is derived from botulinum toxin A to smooth dynamic wrinkles and give a rejuvenated, more awake appearance. Many patients find Dysport to take effect within 1-2 days, and can also last longer than other neurotoxins, up to 5 months for some patients. Like Botox, it contains accessory proteins that may lead to antibody resistance over repeated treatments.


Xeomin (incobotulinumtoxinA) is sometimes referred to as the "naked" neurotoxin since it contains only the botulinum toxin ingredient with no additional proteins or components. This makes it less likely to develop antibodies or resistance that can happen with other neurotoxin treatments over time.

It works similarly to other neurotoxins, but without accessory proteins its formula may be less prone to being broken down by antibodies. For this reason, Xeomin may last a bit longer than 3-4 months for some patients.


Jeuveau (prabotulinumtoxinA-xvfs) was approved by the FDA in 2019, and like Botox is made using a 900-kDa botulinum toxin type A molecule. Jeuveau utilizes Hi-Pure technology which filters out denatured proteins, making it over 95% pure. This purity makes Jeuveau less likely to cause a resistance over time, and also makes it the most precise neurotoxin on the market. Jueveau is also known for its precision and therefore has lower rates of complications like a dropped brow or crooked smile. 


The latest FDA-approved neurotoxin to hit the aesthetic market is Daxxify (daxibotulinumtoxinA). What sets Daxxify apart is its potential to last much longer than existing neurotoxin options - up to 6 months for some patients versus 3-4 months with other neurotoxins.

Which Neurotoxin is Right For Me?

The "best" neurotoxin treatment really depends on your own goals, preferences, and financial considerations. Some key factors to think about:

Treatment Areas - Certain neurotoxins may be more or less effective in particular areas like the forehead/brows based on their diffusion. Make sure to discuss your specific targets with your injector.

Longevity - Those looking for maximum time between appointments and less frequent dosing may opt for Daxxify. However, Botox, Dysport, Jeuveau and Xeomin remain extremely effective when injected on a 3-4 month cycle.  

Antibody Resistance - If you've experienced antibody resistance to Botox, Dysport, or Daxxify in the past, Xeomin or Jeuveau may be a better option since they don't contain accessory proteins.

At NM Aesthetics, the top tox injectors in Arlington, VA, we offer all five neurotoxin treatments so we can develop a fully customized plan for you based on your unique needs and anatomy. Our expert injectors take into account your problem areas, desired results, lifestyle factors, and budget before recommending the neurotoxin that will work best.

Botox, Dysport, Xeomin, Jeuveau and Daxxify have all undergone rigorous clinical testing to prove their safety and efficacy, so you can feel confident about the quality of these products. The real differentiator comes down to your individual treatment goals and the skill of your injector.

Are you ready to enjoy a smoother, line-free, more youthful appearance with neurotoxin injections? Book your consultation at NM Aesthetics today to get started!

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